Topics: Genetic diseases

About the talk: Traditional medicine has only taken us so far in promoting tissue regeneration. Extracellular vesicles (EVs) – cell-drived membranous nano-structures – have been hailed as the next generation in regenerative medicine. EVs ferry hundreds of bioactive molecules such as proteins, lipids and RNAs to synergistically influence the behaviour of multiple target cells in a ...

Ever wondered what it’s like to be a scientist?

About the talk: Sudden cardiac arrest in the young (1-50) is a common condition, affecting 3000 Australians nationally with 90% mortality. In Victoria, the End Unexplained Cardiac Death (EndUCD) registry commenced in 2019, with prospective collection of all out-of-hospital cardiac arrests attended by Ambulance Victoria. These cardiac arrests have comprehensive adjudication against hospital and forensic data, ...

Dr Jessica Orchard, Associate Faculty member at the Centenary Institute, together with Professor Ben Freedman from the Heart Research Institute, have written an article for The Conversation on wearable technologies and heart health.

Centenary Institute researcher and PhD candidate, Dr Julia Isbister, has been awarded the 2022 Ralph Reader Prize for Clinical Science by the Cardiac Society of Australia and New Zealand (CSANZ).

The Centenary Institute’s Agnes Ginges Centre for Molecular Cardiology has celebrated twenty years of world-leading research into the diagnosis, treatment and prevention of genetic heart diseases and sudden cardiac death in the community.

Researchers, including from the Centenary Institute, have reported that ultra-low levels of the dipeptidyl peptidase 9 (DPP9) enzyme could be contributing to immune disorders in children.

The Centenary Institute’s Professor Chris Semsarian AM, Head of the Agnes Ginges Centre for Molecular Cardiology, has talked about his research into cardiovascular disease and sudden cardiac death in young people, in an interview on Radio 2GB’s Healthy Living program.

Dr Jessica Orchard, Research Fellow in the Agnes Ginges Centre for Molecular Cardiology and Heart Foundation Postdoctoral Fellow has been promoted to the Centenary Institute’s Scientific Associate Faculty based on research excellence, productivity and emerging leadership qualities.

Professor Chis Semsarian AM, Head of the Agnes Ginges Centre for Molecular Cardiology at the Centenary Institute and Cardiologist at the Royal Prince Alfred Hospital, has given a headline talk on the genetic basis of cardiovascular disease as a part of Sydney Local Health District’s 'Innovation Week' event.

Dr Richard Bagnall, Head of the Centenary Institute’s Bioinformatics and Molecular Genetics Laboratory, has been interviewed on Radio 2GB’s Healthy Living program.

Researchers from the Centenary Institute have found that concealed cardiomyopathy is an important cause of sudden cardiac death where no cause is found from autopsy – and that genetic testing can help identify cases of concealed cardiomyopathy which provides a cause of death and also helps guide care of surviving relatives.

Professor Christopher Semsarian AM, Head of the Centenary Institute’s Agnes Ginges Centre for Molecular Cardiology has been recognised by the University of Sydney’s Cardiovascular Initiative (CVI) and been presented with an award for ‘Most Collaborative Cardiovascular Researcher’.

The Sydney Morning Herald has reported study findings from the Centenary Institute that found that concealed cardiomyopathy – heart muscle disease that can cause fatal heart rhythms – is an important cause of sudden cardiac death where no cause is found from autopsy.

You may have wondered what makes stem cells so important and why they are needed for medical research.

Professor John Rasko AO, Head of the Gene and Stem Cell Therapy Program at the Centenary Institute has been interviewed by Dr Norman Swan on Radio National’s Health Report about gene therapy treatment for Duchenne muscular dystrophy as well as the status of gene therapy in the clinic generally.

Researchers at the Centenary Institute and the Sydney Local Health District (SLHD) have been awarded $500,000 from CUREator, Australia’s national biotech incubator, to develop new technology to improve the safe and effective delivery of gene therapy.

Professor John Rasko AO, Head of the Centenary Institute's Gene and Stem Cell Therapy Program, has been honoured with the prestigious Proteomass Scientific Society Career Award.

Dr Mehdi Sharifi Tabar, a researcher from the Gene and Stem Cell Therapy Program at the Centenary Institute, has been announced as the recipient of the 2023 Kenyon Foundation Inflammation Award.

Dr Jessica Orchard, a Centenary Institute researcher at the Agnes Ginges Centre for Molecular Cardiology and a Heart Foundation Postdoctoral Fellow, has been interviewed for the latest Medical Journal of Australia (MJA) podcast.

Dr Jessamy Tiffen, a senior member of the Centenary InstituteÕs Melanoma Immunology and Oncology Program has some sage advice for aspiring female scientists in advance of this year's 'International Day of Women and Girls in Science'.

Professor Christopher Semsarian AM, Head of the Agnes Ginges Centre for Molecular Cardiology at the Centenary Institute and Dr Michael J. Ackerman, M.D. (Mayo Clinic) have jointly participated in a live Q&A session on the topic of COVID-19 and genetic heart disease.

Centenary Institute researchers have discovered that genetic testing can identify Ôconcealed cardiomyopathiesÕ in nearly a quarter of sudden cardiac arrest (SCA) survivors who seem to have a normal heart.

Research from the Centenary Institute showing that genetic testing can help identify the cause of sudden cardiac arrest (SCA) in young people who seem to have a normal heart has been featured in the Sydney Morning Herald.

In a momentous breakthrough, Australian scientists have found that humans, and most likely the entire animal kingdom, share important genetic mechanisms with a jelly-like sea sponge that comes from the Great Barrier Reef.

World-leading research into sudden cardiac death (SCD) in young people and multiple sclerosis has been boosted with two Centenary Institute researchers successfully securing prestigious Ideas Grants in the latest round of National Health and Medical Research Council (NHMRC) funding.

Dr Jessica Orchard, a Postdoctoral Fellow at the Centenary Institute and the University of Sydney has written an article for The Conversation following the dramatic collapse of DenmarkÕs Christian Eriksen when his heart stopped during a recent Euro 2021 football match.

Professor Chris Semsarian AM, Head of the Agnes Ginges Centre for Molecular Cardiology at the Centenary Institute and spokesperson for the Cardiac Society of Australia and New Zealand, has been interviewed by the Sydney Morning Herald (SMH) on his response to recent studies linking PfizerÕs COVID-19 vaccine with myocarditis, particularly in young men.

Professor John Rasko AO, Head of the Gene and Stem Cell Therapy Program at the Centenary Institute has featured in a Sydney Morning Herald (SMH) article on gene therapy and its growing emergence into the clinic.

Research led by the Centenary Institute and the Harvard Medical School, Boston, shows that a compound present in current beta blocker treatments could be repurposed to increase efficiency and safety of infantile hemangioma therapies.

For the past four years, the University of Canberra Stars Football Club has raised vital funds for the Centenary Institute in honour of Aaiden Bellingham, who was tragically lost in 2017. Now, they’re back for 2022 with the launch of the annual Bellingham Cup. The annual pre-season tournament focuses on bringing the club together to ...

Associate Professor Mathias Francois established the Centenary Institute’s ‘David Richmond Laboratory for Cardiovascular Development: Gene Regulation and Editing’ back in June 2019. It’s the architecture and complexity of the vascular system in humans that he finds particularly fascinating, especially their mode of assembly during embryonic development.

Hi, I’m Chris and I’m Head of the Agnes Ginges Centre for Molecular Cardiology at Centenary.

Hi I’m Richard and I work in the Molecular Cardiology Program at Centenary.